Gene
ascc3
- ID
- ZDB-GENE-130214-2
- Name
- activating signal cointegrator 1 complex subunit 3
- Symbol
- ascc3 Nomenclature History
- Previous Names
-
- si:ch73-374j3.1
- zmp:0000000854
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have 3'-5' DNA helicase activity. Predicted to be involved in DNA dealkylation involved in DNA repair; DNA duplex unwinding; and cell population proliferation. Predicted to localize to nucleus. Orthologous to human ASCC3 (activating signal cointegrator 1 complex subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, autosomal recessive 81 | 620700 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR004179 | Sec63 domain |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | C2 domain superfamily | DEAD/DEAH box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | Immunoglobulin E-set | P-loop containing nucleoside triphosphate hydrolase | Sec63 domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F8F4
|
1534 | ||||||||||
|
UniProtKB:A0A8M9PJR4
|
2203 |
Interactions and Pathways
No data available
Plasmids
No data available